ISCaM 2023

Session 1

• 02.00 pm

  Keynote - Ralph DeBerardinis (Children's Medical Center Research Institute at University of Texas (UT) Southwestern Medical Center, Dallas, TX, US).
  Metabolic Reprogramming and Cancer Progression in Patients

• 02.40 pm

  Valter Longo (IFOM ETS, the AIRC Institute of Molecular Oncology, Milan, Italy; Longevity Institute, Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA)
  Fasting Mimicking Diet Enhances the Efficacy And Reduces Side Effects of Immune Checkpoint Inhibitors in Cancer Models

• 03.10 pm

  Katiuscia Bianchi (Barts Cancer Institute, Queen Mary University of London, London, UK)
  Altered Metabolism in Obesity Driven Inflammation

• 03.40 pm

  Tea Break

• 04.10 pm

  Paolo Ceppi (University of Southern Denmark, Odense, Denmark)
  Propionate Targets Epithelial-to-Mesenchymal Transition in Non-Small Cell Lung Carcinoma

• 04.25 pm

  Marco Fantuz (Veneto Institute of Molecular Medicine, Padova, Italy)
  Single Nuclei Multi-Omic Approach Reveals Permanent Reprogramming of Exocrine Cells After Pancreatitis

• 04.40 pm

  Flash talks (1-8)
  David Papadopoli | Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada
  Emily Kay | CRUK Beatson Institute, Glasgow, UK
  Giulia Marotta | European Institute of Oncology IRCCS, Milan, Italy
  Elena Rainero | University of Sheffield, UK
  Maxime Toujas | Bordeaux University, INSERM, U1312 BRIC, Pessac, France
  Cloé Tessier | Bordeaux University, INSERM, U1312 BRIC, Pessac, France
  Felipe Jiménez Hernández | Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain
  

• 05.00 pm

  Drinks Reception/Poster session 1

• 07.00 pm

  End of Day 1

Session 2

• 09:30 am

  Maria J. Rodriguez Colman (University Medical Center Utrecht, the Netherlands)
  Metabolism As a Driver of Tumour Phenotypic And Genetic Heterogeneity

• 10:00 am

  Martina Chiu (University of Parma, Italy)
  The Metabolic Microenvironment Imposed by Multiple Myeloma Shapes a Protumour Bone Marrow Niche

• 10:15 am

  Justin Rondeau (Université Catholique de Louvain, Brussels, Belgium)
  Metastasis: A Side Effect of Low-Dose Ionizing Radiation in Breast Cancer Cells?

• 10:30 am

  Coffee break

• 11:00 am

  Thales Y. Papagiannakopoulos (Department of Pathology, New York University Grossman School of Medicine; Laura and Isaac Pelmutter Cancer Center, New York University Langone Health, New York, NY, USA)
  Uncovering the Mechanisms of Disease Progression in Genetic Subsets of KRAS Mutant Lung Cancer

• 11:30 am

  Elena Richiardone (Université Catholique de Louvain, Brussels, Belgium)
  Tumour Metabolic Acidosis: a Key Piece in The Puzzle of Colorectal Cancer Heterogeneity

• 11:45 am

  Nguyen Thi Binh Nguyen (University Medical Center Utrecht, The Netherlands)
  Integrative Multiomics-Imaging Analysis Reveals Intratumoral Phenotypic Heterogeneity: Effect of The Warburg Effect on Tumour Development

• 12:00 pm

  Flash talks (9-16)
  Michael Kossifos | University College London; The Francis Crick Institute, London, UK
  Filipa Martins | NOVA Medical School, Lisbon, Portugal
  Moustafa Ghanem | University of Genoa, Italy
  Hannah Rouse | Queen Mary University London; Barts Cancer Institute, London, UK
  Albert Thommen | The Francis Crick Institute, London, UK
  Zeyad D Nassar | South Australian Immunogenomics Cancer Institute, University of Adelaide, Australia
  Ana Bastos | Université Côte d'Azur, INSERM U1065, Centre Méditerranéen de Médecine Moléculaire
  Donatella Delle Cave | National Research Council, Institute of Genetics and Biophysics, Naples, Italy
  

• 12:30 pm

  Lunch, Poster session 2 & exhibitor viewing

Session 3

• 02:00 pm

  Marco Sandri (Veneto Institute of Molecular Medicine; Department of Biomedical Sciences, University of Padova, Padova, Italy; Department of Medicine, McGill University, Montreal, Canada)
  Novel Players In Cancer Cachexia

• 02:30 pm

  Ersa Gjelaj (The Francis Crick Institute)
  Investigating The Role of Histidine in Myc-Driven Tumourigenesis

• 02:45 pm

  Mohamed Elgendy (University Hospital Dresden, Germany)
  Bridging Cell Survival and Bioenergetics: a Novel Role for Pro-Survival Mcl-1 in Regulating Bioenergetics through Signaling to MTORC1

• 03:00 pm

  Paolo Porporato (Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy)
  Targeting Metabolic Crosstalk Between Muscle and Tumour

• 03:30 pm

  Refreshments

• 04:00 pm

  Stephan Herzig (Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg; German Center for Diabetes Research (DZD), Neuherberg; Chair Molecular Metabolic Control, Technical University Munich, Munich, Germany)
  Connecting Diabetes and Tumour-induced Wasting Syndromes

• 04:30 pm

  Vittoria Raimondi (University of Padova, Italy)
  A Redox-Based Strategy to Overcome Venetoclax Resistance of Acute Myeloid Leukemia Cells

• 04:45 pm

  Fabio Zani(The Francis Crick Institute, London, UK)
  Beyond Sweetness: Sucralose and T cells

• 05:00 pm

  Meet the editors
       Barbara Marte, Nature Senior Editor, London
       Maria Garcia Fernandez, Nature Communications Senior Editor, London

• 05:00 pm

  Poster session 3 and drinks reception

• 07:00 pm

  End of day 2 and Speakers’ dinner

Session 4

• 09:30 am

  Jason W Locasale (Duke University School of Medicine, Durham, NC, USA)
  Targeting cancer metabolism – diet and metabolic therapeutics

• 10:00 am

  Vincenzo Ciminale(University of Padova, Italy)
  Mtor Inhibition Disrupts Redox Homeostasis and Triggers Apoptosis in T-Lymphoblastic Leukemia (T-ALL) cells

• 10:15 am

  Dimitrios Anastasiou (The Francis Crick Institute)
  Roles of Host Metabolism in Liver Cancer

• 10:45 am

  Coffee break

• 11:15 am

  Marc Hennequart (University of Namur, Belgium)
  Loss of ALDH1L2 Expression and Formate Overflow as Biomarkers for Pancreatic Cancer Detection

• 11:30 am

  Vassilis Papalazarou (The Francis Crick Institute)
  Phenotypic Profiling of Solute Carriers Defines Serine Transport in Cancer

• 11:45 pm

  Flash talks (17-24)
  Julie Vignau | Université Catholique de Louvain, Brussels, Belgium
  Ellora Sen | National Brain Research Centre, India
  Annarosa Arcangeli | University of Florence, Italy
  Angela M Otto | Munich Institute of Bioengineering, Technical University of Munich, Germany
  Mariaelena Pistoni | Laboratory of Translational Research, Azienda USL-IRCCS di Reggio Emilia, Italy
  Patricia Nunes | The Francis Crick Institute, London, UK
  Sharavan Vishaan Venkateswaran | The Francis Crick Institute, London, UK
  Giorgia Zadra | Institute of Molecular Genetics, National Research Council, Pavia, Italy
  

• 12:20 pm

  ISCaM General Assembly

• 12:50 pm

  Lunch, Poster session 4 and exhibitors

Session 5

• 2:15 pm

  Mariia Yuneva (The Francis Crick Institute)
  Dissecting Metabolic Vulnerabilities and Heterogeneity Of Tumours

• 2:45 pm

  Shawn Davidson (Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ; Northwestern University, Chicago, IL, USA)
  Spatial assessment of metabolism

• 3:15 pm

  Bob Gillies Lecture: Kevin Brindle (Cancer Research UK Cambridge Institute; Department of Biochemistry, University of Cambridge, Cambridge, UK)
  Magnetic Resonance Imaging of Tumour Metabolism

• 4.00 pm

  Concluding remarks, prizes and end of meeting